Job Details

Join Immatics and shape the future of cancer immunotherapy; one patient at a time!

Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics.

Why Join Us?

• Innovative Environment: Help to pioneer advancements in cancer immunotherapy.

• Collaborative Culture: Be part of a diverse team dedicated to your professional growth.

• Global Impact: Contribute to therapies that make a lasting impact on patients globally.

We are seeking a Manufacturing Associate I to support our Clinical manufacturing team. The Manufacturing Associate I will be responsible for performing complex, highly specialized and time sensitive technical cell manipulation and testing procedures on irreplaceable cellular products during clinical manufacturing.

FLSA Classification: Hourly, Non-Exempt
Schedule: 8:00 AM - 4:30 PM; Monday to Friday; On-site
Reports to: Manufacturing Manager
Location: 13203 Murphy Road Suite 100 Stafford, TX 77477; 1941 East Rd, BBSB 6102 Houston, TX 77054

What You'll Do:

As a Manufacturing Associate I you will play a key role in supporting our clinical manufacturing:

• Possess knowledge of current cGMP.

• Fulfill the operator and verifier roles in performing cell growth and manipulation procedures such as cell enrichment, cell culture, cellular product cryopreservation, cell product thaw/wash.

• Accurately perform procedures in compliance with FDA's Good Laboratory Practices, Good Manufacturing Practices, Good Tissue practices, as well as standards set by other accreditation agencies including but not limited to FACT, CAP, and CLIA.

• Adhere to ALCOAC++ and cGDocP requirements while accurately performing procedures and maintaining documentation in compliance with SOPs.

• Document deviations and events, notify supervisor and quality management personnel in timely manner, and assist in investigation of root cause and any required corrective actions.

• Responsible for aseptic handling of reagents and products to ensure the integrity and sterility of cellular products until final infusion to the patient. Must adhere to special cleaning and gowning requirements for the facility requiring specialized gowning such as masks, sterile jumpsuits, hair and shoe covers.

• Ability to work productively and to participate in a highly creative and fast-paced environment.

Secondary Functions:

• Independently perform calculations to determine cell viability, dilutions, and cell concentrations.

• Completes all appropriate logs and trackers.

• Maintains GMP cleanliness: autoclaving, bleaching liquid waste, removing waste, general cleanliness and organization of the office and facility.

• Maintains knowledge regarding donor evaluation, screening and testing, labeling and product acceptability and release criteria.

• Conducts activities to support study plans, and IQ/OQ/PQs.

• Provide input or feedback regarding change controls, WI, SOPs, study plans, reports, deviations, OOS/OOE, and CAPA's as directed.

• Performs routine equipment maintenance and troubleshooting.

• Prepares and presents manufacturing summaries, as needed.

Required Experience and Education:

• Enrolled in a Biomanufacturing Technology Associate of Applied Science Degree, Biomanufacturing Technology Level 2 Certificate, or equivalent. Or Enrolled in an Associate Degree in Biology, Biochemistry, Biotechnology, Biomanufacturing or other related field.

• Zero (0) to Two (2) years of cell therapy manufacturing experience.

Preferred Experience and Education:

• Bachelor's Degree in Biology, Biochemistry, Biotechnology or other related field.

• One (1) to Two (2) years of cell therapy manufacturing experience.

Competencies

• Initiative

• Problem Solving

• Critical Thinking

• Interpersonal Communication

• Customer Service

• Attention to Detail

Work Environment:

• Typical office environment with moderate noise levels (~20% of work hours). Uses phone, computer, office equipment and supplies on a regular basis.

• cGMP clean room spaces and facilities (~80% of work hours). Grade A/B/C/D GMP environment with associated facility noise levels. Uses cleanroom phone, computer, variety of equipment and reagent/supplies.

• General unclassified laboratory spaces, as needed. Common laboratory equipment and noise levels.

• While performing the duties of this job, the employee routinely handles blood components and is occasionally exposed to temperatures between -196°C and 40°C, liquid nitrogen, liquid nitrogen vapor, dry ice, and carbon dioxide.

Travel required: Travel may be required between the office building and manufacturing facility on a daily basis.

Physical demands:

• Carrying- to transport an object - usually by holding it in the hands or arms but may occur on the shoulder.

• Climbing- moving up or down step stools or ladders while maintaining balance

• Communicating Verbally - expressing or exchanging ideas by means of the spoken word to impart oral information to others to convey detailed spoken instructions or other workers accurately, loudly or quickly.

• Feeling- the ability to detect different materials or temperatures with fingers and hands.

• Gowning- sitting or standing to don or remove sterile PPE.

• Hearing - the ability to hear, understand, and distinguish speech and/or other sounds one-on-one, group or conference, telephone, and other sounds.

• Keyboarding - entering data or text into a computer or other machine by means of a keyboard. Devices include a traditional keyboard, 10 key-pad, touch screens and others.

• Lifting - raising or lowering an object (up to 25 lbs) from one level to another (includes upward pulling). Carrying is to transport an object - usually by holding it in the hands or arms but may occur on the shoulder.

• Near Visual Acuity - clarity of vision at approximately 20 inches or less (working with small objects, reading small print, including the use of computers).

• Pushing - Exerting force upon an object so that the object moves away from the object.

• Pulling - Exerting force upon an object so that the object moves toward the force.

• Sitting - remaining in a sitting position for at least 50% of the time.

• Standing/Walking - remain on one's feet in an upright position at a workstation.

• Stooping - occasional bending the body downward and forward by bending the spine at the waist - requiring full use of the lower extremities and back muscles.

Work authorization/security clearance requirements:

Legal eligibility to work in the United States is required. Immatics participates in E-Verify and all new employees will be subject to the Department of Homeland Security requirements for employment

Affirmative Action/EEO statement:

Immatics is an equal opportunity employer. All employment decisions including the decision to hire, promote, discipline, or discharge, will be based on merit, competence, performance, and business needs.

What do we offer?

At Immatics, we believe in investing in our team's health, safety and well-being. Here's what you can expect if you join Immatics

Comprehensive Benefits:

• Competitive rates for Health, Dental, and Vision Insurance

• 4 weeks of Paid Time off, granted up front each year and prorated for first and last year of employment.

• Sick Time Off - 56 hours

• 12 Paid Holidays

• 100% Employer-Paid Life Insurance up to at 1x annual salary

• 100% Employer Paid Short- and Long-Term Disability Coverage

• 401(k) with Immediate Eligibility & company match...

• You are eligible for 401(k) plan participation as of your first paycheck.

• The company will match 100% of your contributions up to 3% of your base salary for the first two years of employment, 4% for years 2-3 of employment, and up to 5% of your salary from the fourth year onward of continued employment.

• Partially paid Parental Leave for eligible employees. (3 weeks)

• Additional voluntary employee paid coverages including Accident, Hospital Indemnity, and Critical Illness Employee Paid Identity Theft Protection and Pet Insurance.

Professional Growth:

• Opportunities to work with leading experts in the field of T-cell immunotherapy.

• Company provided learning and development opportunities

• Fast paced, high demand collaborative and dynamic environment.